The Global Water Partnership-Central Africa (GWP-CAf), one of the thirteen Regional Water Partnerships, started its activities in Central Africa in 2004 with the Central Africa Technical Committee in short (GWP-CAfTAC). In 2008, the GWP-CAf, Central African Regional Water Partnership (GWP-CAf) was formally established.

To date, GWP-CAf has contributed to the creation of five (05) Country Water Partnerships (CWPs) in five countries in the sub-region: Cameroon, Central African Republic, Republic of Congo, Sao Tome and Principe and Chad. The GWP CAf network is therefore composed of 252 public and private partners from five Central African countries.

In its vision for the 2014-2019 strategy, which is that of a "Central Africa where water security is ensured", the GWP-CAf has set itself the mission of "supporting sustainable development through the promotion and implementation of Integrated Water Resources Management in Central Africa".

The GWP CAf is a non-political, non-denominational and non-profit non-governmental organization, open to all institutions, organizations, associations and research centers that recognize and promote the principles of Integrated Water Resources Management (IWRM) in Central Africa.